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Arabidopsis functional genomics at TIGR
Genomics has produced a revolution in plant biology and genome and EST sequencing projects of various plants are progressing rapidly. The completion of the Arabidopsis genome sequence at the end of the year 2000 was a noteworthy achievement, and the rapid progress that has been made in the sequencing of Rice promises to provide an important additional plant resource for comparative analysis of genes and gene function. A significant challenge in all genome projects is the identification and annotation of the genes and the roles they play in development, disease, and response to environmental stresses.In Arabidopsis, genome sequencing has allowed the identification of approximately 25,500 predicted coding sequences, but significant work remains to provide functional annotation for these. Our goal is to provide experimental validation for these gene predictions and to begin to assign functional roles to genes using DNA microarray technology as a key tool.
